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Maintaining American leadership in artificial intelligence (AI)

A University of Maryland unmanned aircraft delivered a donor kidney to surgeons at the University of Maryland Medical Center for successful transplantation into a 44-year-old woman from Baltimore, who spent eight years on dialysis before undergoing the transplant procedure. This success shows the potential of unmanned aircraft systems (UAS) delivering organs faster, safer, and with more availability than traditional transport methods.

The patient who was discharged from UMMC on Tuesday said “This whole thing is amazing.”

The momentous flight was a collaboration between transplant physicians and researchers at the University of Maryland School of Medicine (UMSOM) in Baltimore; aviation and engineering experts at the University of Maryland (UMD); the University of Maryland Medical Center; and collaborators at the Living Legacy Foundation of Maryland (The LLF).

Among the many technological firsts of this effort include: a specially designed, high-tech apparatus for maintaining and monitoring a viable human organ; a custom-built UAS with eight rotors and multiple powertrains to ensure consistently reliable performance, even in the case of a possible component failure; the use of a wireless mesh network to control the UAS, monitor aircraft status, and provide communications for the ground crew at multiple locations; and aircraft operating systems that combined best practices from both UAS and organ transport standards.

“We had to create a new system that was still within the regulatory structure of the FAA, but also capable of carrying the additional weight of the organ, cameras, and organ tracking, communications, and safety systems over an urban, densely populated area – for a longer distance and with more endurance,” said Matthew Scassero, MPA, director of UMD’s UAS Test Site, part of A. James Clark School of Engineering. “There’s a tremendous amount of pressure knowing there’s a person waiting for that organ, but it’s also a special privilege to be a part of this critical mission.” 

Designing a UAS organ delivery system
To create a UAS designed to carry an organ and provide real-time monitoring of its condition, Scalea partnered with several medical technology companies to design and develop the Human Organ Monitoring and Quality Assurance Apparatus for Long-Distance Travel (HOMAL; patent pending). It measures and maintains temperature, barometric pressure, altitude, vibration, and location (via GPS) during transportation and transmits the information to the smartphones of transplant personnel.

The unmanned aircraft and operating systems were designed by UMD UAS Test Site engineers to meet the rigid medical, technical, and regulatory demands of carrying a donor organ for human transplantation.

“We built in a lot of redundancies, because we want to do everything possible to protect the payload,” said Anthony Pucciarella, director of operations at the UMD UAS Test Site. These safeguards included backup propellers and motors, dual batteries, a backup power distribution board, and a parachute recovery system (in case the entire aircraft fails). 

Maryland faculty and researchers believe this prototype organ transport blazes a trail for the use of UAS to expand access to donated organs, improving outcomes for more people in need of organ transplants.

“As a result of the outstanding collaboration among surgeons, engineers, the Federal Aviation Administration (FAA), organ procurement specialists, pilots, nurses, and, ultimately, the patient, we were able to make a pioneering breakthrough in transplantation,” said Joseph Scalea, MD, assistant professor of surgery at UMSOM, project lead, and one of the surgeons who performed the transplant at UMMC.

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Prior to this landmark organ delivery flight, the Maryland partners worked together to develop and test the UAS by first successfully transporting saline, blood tubes, and other materials, and then by transporting a healthy, but nonviable, human kidney. These test flights were preceded in 2016 by the state of Maryland’s first civil unmanned aerial delivery of simulated medical cargo, a collaborative effort between UMD’s UAS Test Site and the University of Maryland Shore Regional Health in Easton, Maryland, to illustrate how the use of UAS could radically change medical care and impact the lives of real people.

“This history-making flight not only represents a breakthrough from a technological point of view, but provides an exemplary demonstration of how engineering expertise and ingenuity ultimately serve human needs – in this case, the need to improve the reliability and efficiency of organ delivery to hospitals conducting transplant surgery,” said Darryll J. Pines, Ph.D., dean of the A. James Clark School of Engineering and Nariman Farvardin Professor of Aerospace Engineering. “As astonishing as this breakthrough is from a purely engineering point of view, there’s a larger purpose at stake. It’s ultimately not about the technology; it’s about enhancing human life.”

DISCLOSURE: Dr. Scalea is founder of a private data analytics company, Transplant Logistics and Informatics. Funding for this research was provided by the Maryland Technology Development Corporation (TEDCO) with additional resources from the UAS Test Site, UMSOM, UMMC, the University of Maryland, Baltimore, Office of Technology Transfer, and the City of Baltimore.

SOURCE: http://www.todaysmedicaldevelopments.com/Article/nist-artificial-intelligence-manufacturing-050819

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By |2019-05-08T07:00:00-04:00May 8th, 2019|Categories: Medical Development|Tags: , |0 Comments

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